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139 The causal relationship between use of acetaminophen and the occurrence of asthma has been questioned, 140 but the consensus is that a relationship exists 141,142 and a population-wide increase in asthma of more than 40% may be caused by the use of acetaminophen
This dual-phase injury not only impacts the initially ischemic tissue but also induces systemic responses that contribute to distant organ damage, particularly in the liver, kidneys, and lungs [4]
In 2006, Bruno et al

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