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Approximately one year later, he experienced a severe worsening of his previously very mild neuropathy, and lab evaluation yielded a serum B12 of 220 pmol/l (which is normal, remember!?), but an elevated serum MMA of 1300 nmol/l, supporting the existence of true B12 deficiency

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The increased migration to the sites of inflammation is also determined by a reshaping of the extracellular matrix through the action of metalloproteins MMP-1 and MMP-3, and the over-expression of adhesion molecules such as MAcCAM-1 and integrin 44

For example, benfotiamine helps process sugar safely, omega-3s lower inflammation, ALA protects against oxidative stress, and B vitamins support metabolism and repair