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Downregulation of Cx43 has been observed in both human and animal models of heart failure (Dupont et al., 2001
Archives of Medical Science 17: 252257
Collagen is very beneficial for the growth of hair, skin, nails, and bone health (2)
Heme levels can also be regulated by the rate of catabolism, which is controlled by heme oxygenase 1 (HO-1), the enzyme responsible breaking down heme into biliverdin, carbon monoxide, and iron
