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In the liver, choline is converted into betaine, which provides methyl groups that help transform homocysteine into methionine.11 This matters because elevated homocysteine is a well-established risk factor for cardiovascular disease, linked to arterial plaque, blood clots, and stroke.38 While folate and vitamin B12 also contribute to this process, choline-derived betaine may provide as much as 60% of the methyl groups needed to keep homocysteine levels under control.11 By helping regulate homocysteine, adequate choline intake contributes to healthier blood vessels and reduced cardiovascular risk

Plasma Lipidomic analyses in cohorts with mTBI and/or PTSD reveal lipids differentially associated with diagnosis and APOE 4 carrier status
[DOI] [PMC free article] [PubMed] [Google Scholar] 149.You X.Y., Zhang H.Y., Han X., Wang F., Zhuang P.W., Zhang Y.J
