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Riboflavin deficiency may be associated with an increased risk of anemia during pregnancy, and RCTs conducted in pregnant populations have demonstrated that the inclusion of riboflavin with other micronutrient supplements (namely iron and folic acid) leads to greater improvements in hematological parameters, such as hemoglobin concentration, RBC count, and anemia prevalence (reviewed in 62)

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This finding is still debated and the clinical significance for people taking moderate injectable doses (which bypass gut metabolism) is unclear