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Embryofetal Toxicity Some epidemiologic studies suggest that exposure to sulfamethoxazole/trimethoprim during pregnancy may be associated with an increased risk of congenital malformations, particularly neural tube defects, cardiovascular malformations, urinary tract defects, oral clefts, and club foot

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In humans, anteriorposterior tonsillar pillars and the posterior pharyngeal wall are the most sensitive areas for eliciting the swallow reflex
