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While some studies suggest that exercise leads to substantial improvements in PTSD symptoms, others report minimal effects, particularly in populations with higher levels of comorbidity or more severe PTSD symptoms

However, since increased glutamate in striatum has been documented in schizophrenia before D 2 treatment, some glutamatergic agents for patients that failed D 2 blockers and have persistently increased glutamate may still have a role [136]

2011 Jul 4

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