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The lipid peroxidation is a free radical-driven reaction that primarily affects polyunsaturated fatty acids (PUFAs) in cell membranes, the product of which gradually increases during the ferroptotic cell death, from the initial lipid hydroperoxides (LOOHs) to the later production of malondialdehyde (MDA) and 4-hydroxynenoal (Kagan et al., 2017)

Highlights of the Expert Panel Report 2: Guidelines for the Diagnosis and Management of Asthma

2, 719 (CRC Press, 2006)

While the compounds differ significantly in structure and mechanism, both
