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It has also been proposed that oxidative stress may promote malaria-induced thrombocytopenia, since there was a negative correlation between the number of platelets and levels of lipid peroxidation in malaria patients ( Several clinical trials have been performed to test the efficacy of the antioxidant N-Acetylcysteine (NAC) as an adjunctive treatment for severe malaria

Dunning, C

Overdosing on B vitamins may increase the risk of side effects and allergic reactions

However, excessive MMP activity can lead to increased collagen degradation and weakening of the ACL
