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Oxidative stress related to iron overload markedly increases malondialdehyde, a marker of lipid peroxidation [85], and high levels of myeloperoxidase released by activated leukocytes and neutrophils, causing endothelial dysfunction and liver injury [86]

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To find a more effective method for the cure and treatment of HCC, research for a better understanding of the mechanism involved in the development of cancer, OS-induced damage, and the effects of antioxidants is urgently required (Wang et al., 2016)