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But animal studies extending up to 6 months show no organ toxicity or adverse histological changes (Sikiric et al., Toxicology and Applied Pharmacology, 2019)

doi: 10.1517/13543784.2015.993753

Matrix-free and material-enhanced laser desorption/ionization mass spectrometry for the analysis of low molecular weight compounds

Several FDA-approved anti-cancer drugs, including sorafenib, can induce ferroptosis by inhibiting SLC7A11 activity, even though they also elicit apoptosis in preclinical studies [195]