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2010;5:e9252
(2013) 58(4):98996.e1
12.6 Pathways of biliverdin production from heme by chain-opening and bilirubin production by reduction of biliverdin (Reproduced with permission from Odell [15]) After its formation in reticuloendothelial cells, bilirubin is released into the bloodstream, where it is transported bound to albumin via one primary and two secondary binding sites
At present, the only effective drug recombinant tissue plasminogen activator is limited by its indications, and its clinical application rate is not high
