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Diagnostic strategies for ME/CFS Since the Centers for Disease Control and Prevention (CDC) formally named ME/CFS and established its first diagnostic criteria in 1988, the diagnostic criteria have evolved through various editions of clinical case definitions [17]

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Key amino acids contribute to fibrotic progression
The two primary endogenous ketone bodies are acetoacetate (AcAc) and beta-hydroxybutyrate (BHB), which are interconverted in the final step in ketogenesis in the liver and the first step in ketolysis in peripheral tissues
