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Description
10.1007/PL00006984 J
Mit tartalmaz a Herbadoctor Liposzms Glutathione
found that signal transducers and activators of transcription 3 (STAT3) promote MYC expression in tumor cells in AML, which in turn regulates the transcription of amino acid transporter SLC1A5, promotes Gln metabolism in AML cells, and oxidative phosphorylation (OXPHOS) of leukemia stem cells (LSCs)
Therefore, we hypothesize that LA can reactivate Nrf2 by dissociating it from Keap1 and phosphorylating Nrf2 itself, although the mechanisms need further investigation
