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Cardiopulmonary bypass (CPB) is related to multiple effects that may contribute to post-operative myocardial injury and cardiac dysfunction, including ischemiareperfusion injury after removal of the aortic clamp, the subsequent generation of reactive oxygen species, and increased production of inflammatory mediators [2, 3]
Glatzle, D., Vuilleumier, J
Some cases exhibit all the signs of depression but at lesser severity or a shorter time frame than a clinical diagnosis
