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Description
The PDHc catalyzes the oxidative carboxylation of pyruvate which serves as the entry point for carbohydrates into the TCA cycle as acetyl-CoA
10 This finding raises the question of whether the activation of p70S6K1 by OSI-906 is through IGF-1R inhibition or it is a non-specific effect of OSI-906
Bos KJ, Holmes DF, Meadows RS, Kadler KE, McLeod D, Bishop PN
Step 2: Clean Both Vial Stoppers Wipe the rubber stopper of both the peptide vial and the bacteriostatic water vial with separate fresh alcohol swabs
