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Pladen uses commercially available products under Korean regulatory framework

T cell migration, differentiation, and activation are primarily driven by DCs and macrophages [56]

Kim-Howard X, Sun C, Molineros JE, Maiti AK, Chandru H, Adler A, Wiley GB, Kaufman KM, Kottyan L, Guthridge JM, Rasmussen A, Kelly J, Snchez E, Raj P, Li QZ, Bang SY, Lee HS, Kim TH, Kang YM, Suh CH, Chung WT, Park YB, Choe JY, Shim SC, Lee SS, Han BG, Olsen NJ, Karp DR, Moser K, Pons-Estel BA: Allelic heterogeneity in NCF2 associated with systemic lupus erythematosus (SLE) susceptibility across four ethnic populations

13 ISGs are clear or low-viscosity liquids before administration, but they convert into a viscous gel in response to nasal physiological conditions (pH, temperature, and ionic change)
