enzyme-catalysed conjugations of glutathione with unsaturated compound doi Glutathione-Mediated Conjugation Anticancer Drugs: An Overview of Reaction Mechanisms and Biological Significance for Drug Detoxification and Bioactivation Glutathione Metabolism - an overview
Description
In laboratory models, this has been linked to reduced accumulation of senescent cells and possible improvement in tissue function
That said, because large-scale, long-term human trials are limited, its complete safety profile is not yet fully understood
Genome-wide CRISPR screens reveal synthetic lethal interaction between CREBBP and EP300 in diffuse large B-cell lymphoma
Additionally, educational programs and lifestyle interventions are essential to acknowledge the prevalence of this new clinical entity
