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Although we identified a likely link between the Na + and carnitine sites, further structural and functional investigations will be necessary to define the precise details of how coupling between the Na + binding and structural change at the carnitine-binding site is mediated

Our group has recently shown that changes in maternal dietary DHA levels may impact differently on the ECS and molecular markers highlighted by increased synaptophysin levels in the neonate brain, CB1/2 receptor levels in dams and neonates brain, glial fibrillary acidic protein (GFAP) levels, and protein kinase A (PKA) phosphorylation in the cortex and ERK phosphorylation in the hippocampus of the progeny (Isaac et al., 2021)

BAT is a metabolically active fat tissue that generates heat by uncoupling the mitochondrial proton gradient essentially running the cellular energy production process "backwards" to generate heat rather than ATP

Follicular cells of the thyroid gland are also innervated by sympathetic fibers containing NE, which can influence the mitotic response to TSH stimulation (245)