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10.1002/ibd.21814 Inflamm

For instance, a high acetyl-CoA/CoA ratio in the mitochondrial matrix inhibits pyruvate dehydrogenase (PDH) that catalyzes the oxidative decarboxylation of pyruvate to acetyl-CoA (Pietrocola et al., 2015)

So, while its not specifically used as an endurance supplement, it can protect us from getting sick which can decrease our endurance capabilities

During autophagy mitochondria elongate, are spared from degradation and sustain cell viability
