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Its levels decrease as a result of aging, stress and exposure to toxins
A 2020 human clinical trial found that cosmetics containing Artemisia Annua Extract increased stratum corneum hydration and reduced transepidermal water loss while also calming redness and inflammation over four weeks of use

The odds ratios for ASD diagnosis following APAP exposure were striking, depending on the comparisons made, exceeding 20-fold in some cases [46]

Between mild and severe patients, the AUCs of the PE-P 18:0-20:3, PE-O 16:0-20:4, and TAG 54:4-FA22:4 were 0.725, 0.763, and 0.738, respectively ( Figures 5BD )
