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Metastasis, the spread of cancer cells from the primary tumor to distant sites, is a hallmark of cancer and a major cause of cancer-related mortality [117]

5-Amino-1MQ is a small-molecule quinolinium compound that has been the focus of metabolic and enzymatic research, particularly in relation to its potential role in inhibiting nicotinamide N-methyltransferase (NNMT), an enzyme implicated in metabolic regulation and obesity-related studies

First-in-man controlled rewarming and normothermic perfusion with cell-free solution of a kidney prior to transplantation

GCLM is enzymatically inactive but plays an important regulatory function by lowering the K m of GCL for glutamate and raising the K i for GSH (Huang et al., 1993a