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Consistent with these phenotypes, NINJ1 knockdown also inhibited other erastin-induced molecular features of ferroptosis, including membrane rupture (Fig

These drugs are released in response to low pH in acidic microenvironments and are taken up by endocytosis

Endothelial dysfunction may be defined as impairment that is characterized by a shift in the actions of the endothelium toward reduced vasodilation, a proinflammatory state, and prothrombotic settings