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Description
PM: Plasmatic membrane

6.3 Broad clinical potential of targeting ferroptosis in neurodegeneration Targeting ferroptosis offers a novel approach to neuroprotection by preserving cellular integrity, modulating inflammation, and enhancing antioxidant defenses

Lancet 378 , 412419 (2011)

CIPN affects sensory, motor and autonomic nerves and is one of the most common adverse events caused by chemotherapeutic agents, which in severe cases leads to dose reduction or treatment cessation, with increased mortality
