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[DOI] [PubMed] [Google Scholar] 103.Han L, Hiratake J, Kamiyama A, Sakata K

Unlike other breast cancer subtypes, TNBC lacks therapeutic targets and is unresponsive to typical hormonal and HER2-based therapies

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For example, the NRF2-specific activator 4-octyl itaconate significantly reduces cisplatin-induced ferroptosis by activating the NRF2/HO-1 signaling pathway (Zhang et al., 2024)
