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Its required for the breakdown of body fat, as well

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In Atg7-deficient mice, the loss of autophagy in hematopoietic stem cells not only leads to increased aberrant myeloid expansion, resulting in severe myeloid dysplasia and infiltrating myeloid blast cells evoking AML [18] but can also activate the NOTCH signaling pathway, blocking HSC differentiation and leading to a leukemic phenotype [19]

Even when youre burning a ton of calories each day, you wont necessarily burn off fat