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Morphologically, ferroptosis is characterized by necrotic-like features, including loss of mitochondrial cristae, increased membrane density, outer membrane rupture, and reduced mitochondrial volume, while preserving plasma membrane integrity during early stages and maintaining normal nuclear morphology

Sterile Water for Injection contains no preservatives and is strictly single-use the vial must be discarded after a single access

The same pattern likely applies to both CagriSema and tirzepatide, though long-term discontinuation data for both is limited