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10.2147/NDT.S5212 212 SpoorenA.KolmusK.LaureysG.ClinckersR.De KeyserJ.HaegemanG.et al

These symptoms markedly reduce quality of life and are associated with stress-induced psychological sequelae that contribute to anxiety, depression, low self-esteem, and relationship strain

What are reactive oxygen species (ROS)

Sirtuins, particularly SIRT1, need NAD+ as a cofactor for protein deacetylation
