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The variant, TT and CT alleles of this polymorphism may have altered TXN2 expression which may compromise its functionality leading to oxidative stress

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S-glutathionylation can occur chemically or fermentatively via glutathione S-transferase (GST), peroxiredoxins, and occasionally glutaredoxins [130]
A study showed that fibronectin, acting via its receptor integrin 51, regulates angiogenic pathways that are distinct from VEGF-mediated angiogenic pathways 83
