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Symptoms of B12 deficiency may include: Depression Fatigue Trouble concentrating Confusion Memory problems Headaches Mood changes Vitamin B12 is essential for red blood cell production, so long-term deficiency can lead to anemia, which can cause fatigue, shortness of breath, and an irregular heartbeat

This includes checking lab results and symptoms

One study, published in 2010 by Jason Tonley and other researchers at several clinics and universities in Los Angeles, describes a different approach for athletes
