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We also found distinct GM/WM differences in cuprizone response

Bertrand PP, Kunze WA, Bornstein JC, Furness JB, Smith ML
Allin BSR, Dumann E, Fawkner-Corbett D, Kwok C, Skerritt C, Paediatric Surgery Trainees Research Network (2018) Systematic review and meta-analysis comparing outcomes following orchidopexy for cryptorchidism before or after 1 year of age

However, the thicker size may not be suitable for routine dosing or for people with needle anxiety or high sensitivity
