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The compound does not appear to cause physiological dependence, but the durability of its effects has not been studied in withdrawal protocols.

The nematode homolog of NFE2L2, SKN-1, is a key regulator of mitobiogenesis and has a role in the control of the expression of the mitophagy receptor DCT-1/NIX in worms [215]

3- Enhanced Cognitive Function A vitamin B12 deficiency can affect cognitive function, leading to memory problems, difficulty concentrating, and even confusion