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Without ongoing B12 replacement, deficiency and symptoms will typically recur within months to years of discontinuation

A natural product-derived nanozyme regulator induced chemo-ferroptosis dual therapy in remodeling of the tumor immune microenvironment of hepatocellular carcinoma

The most well-established among them appears to be nuclear factor erythroid 2-related factor 2 (Nrf2), which is likely activated by redox status changes of the kelch-like ECH associated protein 1 (Keap1) induced by NAPQI
