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Arendt J, Skene DJ

6.3 Mechanistic understanding and complex interactions Although substantial progress has been found in recognizing the core pathways by which exercise may exert therapeutic effectsnamely through the regulation of oxidative stress and HPA axis functionour insight of the complicated relationship between these mechanisms continues to be incomplete

[Preprint] bioRxiv 28;2020.02.20.958249 bioRxiv 253 RnnbckL.HanssonE

Its important to highlight that berberine, being a supplement, is not under regulatory scrutiny
