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Tissue samples were examined for macroscopic damage assessed by a single observer (M.S.) blinded to characteristics or treatment of the animal being studied, according to previously described criteria (Mourelle et al, 1996) that takes into account (1) presence of adhesions (score 02), (2) strictures (score 03), (3) ulcers (score 03), and (4) wall thickness (score 02)

Chung B, Segrest J, Smith K, Griffin F, Brouillette C

Oxidative stress reduces this ratio, overwhelming GRX activity and driving irreversible protein oxidation linked to cell death (25)

As such, a B12 boost can help you quite a bit if youve been feeling fatigued, but only if a B12 deficiency is the reason