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Specifically, GGCT has been confirmed to activate the PI3K/AKT/mTOR signaling, thereby driving the malignant progression of ovarian cancer, hepatocellular carcinoma, and breast cancer [11,12,13]

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IGF-1 enhances NO production by eNOS and upregulates antioxidant enzymes, such as glutathione peroxidase (GPX) and superoxide dismutase (SOD)

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