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Description
Jumping from 0.25 mg to 1.0 mg because you are "not feeling anything" is a reliable way to spend the next week unable to keep food down

Avoid self-administering or altering the dosage without medical guidance

This is the gold-standard way to answer does the oral form actually get in. What they found: ~38.4% oral bioavailability, with a half-life around 6.9 hours oral and 3.8 hours IV
Furthermore, standardized research materials help laboratories maintain consistency across ongoing investigations
