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Unter Bercksichtigung des weit verbreiteten Vorliegens von endothelialem Vaskulaturgewebe im Krper und der essentiellen Rolle des Endothels fr die organprotektiven Wirkungen kann NaBPC157 bei verschiedenen Organlsionen als organprotektives Mittel verwendet werden

Heme depletion Heme, essential for oxygen transport, cellular respiration, and gene regulation, is mainly produced by erythroblasts and hepatocytes

Of note is that in CF an intrinsic downregulation of the antioxidant response regulator and NF-B antagonist Nuclear Factor Erythroid 2-related factor 2 (Nrf2) is described (Moliteo et al., 2022)

In several preclinical studies, BPC157 reduced the severity of gut injuries, reversed damage from NSAIDs, and even supported nerve regeneration