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Vitamin B deficiencies manifest themselves in the form of various neurological disorders and a wide spectrum of pathological conditions (e.g., beriberi disease, pellagra, megaloblastic anemia, peripheral neuropathy, dermatological disorders, and inflammation of the tongue, stomach, and mucous membranes [44]

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This dynamic character of the cellular metabolic network appears enhanced in cancer cells, in order to increase the adaptive phenotype and to maintain both viability and uncontrolled proliferation

For instance, a randomized controlled trial by Soininen et al