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Nature 498 , E8E10 (2013)

Farbers pioneering use of antifolate drugs established cancer chemotherapy, and another folate antagonist, methotrexate, remains a key component of childhood acute lymphoblastic leukemia (ALL) treatment, with a cure rate of up to 90% when combined with l-asparaginase

The determination of lactate concentrations at rest or following exercise has become a diagnostic tool for mitochondrial myopathy [22, 23]

Han Q, et al
