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For instance, surface modification with Tet-1 peptide facilitates blood-brain barrier penetration for glioblastoma and Alzheimers therapy, while PLGA-TPGS (d--tocopheryl polyethylene glycol succinate) nanoparticles exhibit preferential accumulation in hepatocellular carcinoma (HepG2) cells, significantly improving antitumor efficacy and reducing systemic toxicity in vivo [98, 99]
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It also models the space impact on the spacecraft faces and systems during flight into orbit by using the Jenson and Cain model (212)
