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napus (Smeets et al., Elsholtzia splendens , there was increased expression of APX in leaves while in Withania somnifera it was variable according to concentration of metal ions (Peng et al., Nicotiana tabacum and Typha angustifolia , cadmium stress led to changed and unchanged expression of APX isoforms respectively while in Typha leaves, chromium and lead stresses did not induce any change in APX expression (Bah et al., Zea mays led to variable expression of APX (Ekmeki et al., Eichhornia crassipes (Malar et al., Vigna radiata under Cadmium Chloride stress (Roychoudhury and Ghosh, V
However, favoring the theory of hyperhomocysteinemia-induced platelet activation, in vitro studies have proposed that, besides its direct cytotoxicity that damages endothelial cells (Dudman et al, 1991
Vitamin B 12 is still the subject of intense research and, in particular, its role in preventing these irreversible neurological lesions remains unclear

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