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developed a dual-target ADC for EpCAM and CLDN3, which requires high co-expression of both antigens on tumors for effective killing, exhibiting minimal toxicity to normal cells that only highly express EpCAM but have low CLDN3 levels, thereby alleviating the toxicity limitations of single-target EpCAM ADCs [138]

Tardiolo G, Bramanti P, Mazzon E

At Granite State Gastroenterology, we hear this question often, and its a great opportunity to set the record straight on diverticulitis: what it actually is, what causes it, and what the current research really says
