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Such phosphorylative events increase histone acetylation and decrease DNA methylation of PGC-1, NRF1, NRF2, Tfam, UCP2, and UCP3 promoters (Marin et al., 2017) inducing mitochondrial biogenesis

A: Morning and night

Effect of lycopene application in rats with experimental diabetes using lipoprotein, paraoxonase and cytokines

10 Diabetic retinopathy (DR), occurred in 22% of diabetes patients and 6% suffer from vision threatening DR which might lead to irreversible vision impairment even blindness
