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Hence, more investigations are needed to assess other signaling molecular pathways involved in MTX-induced intestinal injury to develop novel strategies for amelioration of intestinal injury induced by MTX

For example, one study showed that in omental but not subcutaneous cells, GCs decreased insulin-stimulated glucose uptake, 32 but whether this was due to decreased insulin signaling remains to be determined

Int J Biol Macromol 209(Pt A):10201031

Mutat Research/Fundamental Mol Mech Mutagenesis
