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The ECL assay may be additionally valuable because it does not use radioactivity, is approved to equip other IAb (insulin autoantibodies, IA-2A and ZnT8A) assays with high affinity specificity with the same format, and is capable of large throughput with low cost, especially with its unique advantage of multiplexing to combine multiple autoantibody assays in one single well [15]

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Additionally, a potential drug binding site can also be predicted based on previous mutagenesis studies that allowed the identification of residues implicated in the transport of doxorubicin, vincristine, and etoposide