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Ethics statement The study involving animals was reviewed and approved by the Ethics Committee on Animals Experimentation Pays de Loire (accreditation number 3455)

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Ammar et al

Mitochondria are also involved in key cellular functions such as Ca 2 + homeostasis, heme biosynthesis, nutrient metabolism (Cheng and Ristow, 2013), steroid hormone biosynthesis, removal of ammonia, integration of metabolic and signaling pathways for cell death and autophagy (Hammerman et al., 2004
