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cocaine, for example, is used as a local anesthetic (Chapter 2), and amphetamines and methylphenidate are used in low doses to treat attention deficit hyperactivity disorder and in higher doses to treat narcolepsy (Chapter 12)

Blocking was done using 5% horse serum for 30 min

The consensus guidelines recently elaborated by the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, and the American Society of Anesthesiologists support the use of KET for chronic pain, but with different degrees of evidence for different conditions and dose ranges (Jevtovic-Todorovic et al., 2001

Tonmya is a sublingual formulation with direct action on the brain to target fibromyalgia sleep and pain