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The PKA and EPAC2 pathways are triggered by both receptors'activation of adenylate cyclase, which raises intracellular cAMP and causes insulin synthesis and release, cellular proliferation, and antiapoptotic effects

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doi:10.1016/j.jcte.2018.01.003

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A Combined Preclinical Therapy of Cannabinoids and Temozolomide against Glioma

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