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CT26 cells (5 10 5 in 50 L serum-free RPMI medium) were injected subcutaneously (s.c.) into the right flank of the animals
Severe skin reactions, generalized bone marrow suppression [see Warnings and Precautions (5.11), Adverse Reactions (6.1)], a specific decrease in platelets (with or without purpura), and hyperkalemia are the most frequently reported severe adverse reactions in elderly patients
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